P7912

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Voltage-gated Ion Channels > Calcium Channel Modulators > Inhibitors and Activators
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P7912

Sigma

Phloretin

≥99%


Synonym:	β-(4-Hydroxyphenyl)-2,4,6-trihydroxypropiophenone, 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone, 2′,4′,6′-Trihydroxy-3-(4-hydroxyphenyl)propiophenone
CAS Number:	60-82-2
Linear Formula:	C₁₅H₁₄O₅
Molecular Weight:	274.27
Beilstein Registry Number:	1887240
EC Number:	200-488-7
MDL number:	MFCD00002288
PubChem Substance ID:	24278652

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Description

Biochem/physiol Actions

Blocks L-type Ca²⁺ channels; activates Ca²⁺-activated K⁺ channels in amphibian myelinated nerve fibers.

Properties

assay	≥99%
mp	~260 °C
storage temp.	2-8°C

Safety

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
WGK Germany	3

References

reference	Cseh, R. and Benz, R., Biophys. J. 77, 1477, (1999) Abstract
	Mizuma, T. and Awazu, S. Biochim. Biophys. Acta 1425, 398, (1998) Abstract
Merck	Merck 13,7411
Beilstein	Beil. 8,IV,3518

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